Gastroenterology

Developed Formulas
Benefits
  • Improves digestion of macronutrients 
  • Supports lactose digestion
  • Supports gastric function
  • Helps alleviate bloating
  • Antacid activity
Gastroenterology
Microbac
Gastroenterology
In vitro test
Gastroenterology
Allergen Free
Gastroenterology
Orosoluble
Components

Lacticaseibacillus rhamnosus LR06 (DSM 21981)
Lactiplantibacillus plantarum LP14 (DSM 33401)
Calcium carbonate
Kiwi Extract

Label Claim
Effective nutraceutical combination
Scientific Rationale

BIFIDIGEST® is a probiotic food supplement uniquely formulated for the rebalancing of intestinal microflora and the support of healthy digestion. It combines microencapsulated gastro-protected probiotic strains with calcium carbonate and Kiwi extract, each component contributing to its overall effectiveness:

  • Lacticaseibacillus rhamnosus LR06 and Lactiplantibacillus plantarum LP14: These strains have been clinically studied for their effectiveness in treating E. coli and other intestinal pathogens [1,2]. Both LR06 and LP14 are notable for their metabolic production of a wide range of enzymes, including lipases, proteases, oxidases, and phosphatases. These enzymes are crucial for their ability to aid in the digestion of various substances like lactose [3].

  • Kiwi Extract: Known for being rich in Actinidin, an enzymatic protein, Kiwi extract plays a significant role in enhancing digestive function. It acts directly in the stomach to boost food catabolism, helping to prevent fermentation and the consequent bloating. Additionally, the fibers present in the Kiwi phytocomplex contribute to its prebiotic effects, which support the growth of beneficial gut bacteria [4-8].

  • Calcium Carbonate: Included for its ability to relieve heartburn, indigestion, and other stomach problems. Calcium carbonate works by neutralizing excess stomach acid, providing relief from these common digestive discomforts.

The combination of these components makes BIFIDIGEST® a comprehensive solution for supporting digestive health and maintaining a balanced gut microbiome.

Bibliography

1.  Deidda F, et al. How Probiotics may Kill Harmful Bacteria: The in vitro Activity against Some Haemolytic Strains. J Prob Health, 2020. Vol. 8 Iss.2 No: 216.  DOI: 10.35248/2329-8901.20.8.216

2. Mogna L. et al. Assessment of the in vitro inhibitory activity of specific probiotic bacteria against different Escherichia coli strains. J Clin Gastroenterol. 2012; 46 Suppl:S29-32

3. Internal Probiotical data

4. Bayer SB, et al. Putative mechanisms of kiwi fruit on maintenance of normal gastrointestinal function. Crit Rev Food Sci Nutr 2018, 58(14): 2432-2452. Doi: 10.1080/10408398.2017.1327841

5. Kaur L, et al. Influence of Kiwi fruit on protein digestion. Adv Food Nutr Res 2013 68:149-167. Doi: 10.1016/B978-0-12-394294-4.00008-0

6. Chalabi et al. Proteolytic activities of Kiwi fruit actinidin (Actinidia deliciosa cv. Hayward) on different fibrous and globular proteins: a comparative study of actinidin with papain. 2014 Apr;172(8):4025-37. Doi: 10.1007/s12010-014-0812-7

7. Kaur L, et al. Actinidin enhances protein digestion in the small intestine as assessed using an in vitro digestion model. J Agric Food Chem. 2010 Apr 28;58(8):5074-80. Doi: 10.1021/jf903835g

8. Weir et al. Efficacy of actinidin-containing Kiwi fruit extract Zyactinase on constipation: a randomised double-blinded placebo-controlled clinical trial. Asia Pac J Clin Nutr. 2018;27(3):564-571. Doi: 10.6133/apjcn.122017.03

9. Del Piano et al. Evaluation of the intestinal colonization by microencapsulated probiotic bacteria in comparison with the same uncoated strains. J Clin Gastroenterol. 2010 Sep;44 Suppl 1:S42-6. DOI: 10.1097/MCG.0b013e3181ed0e71

Associations