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PROBIAL KIDS Flora Forte

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Pediatrics

Developed Formulas
Benefits
  • Antipathogenic activity
  • Anti-inflammatory activity
  • Helps protect intestinal cells
Pediatrics
Ready to market
Pediatrics
Microbac
Pediatrics
In vitro test
Pediatrics
Hydrosoluble powder
Pediatrics
Allergen Free
Pediatrics
Real time stability
Components

Lacticaseibacillus paracasei subsp. paracasei LPC00 (LMG P-21380)
Lacticaseibacillus rhamnosus LR04 (DSM 16605)
Bifidobacterium breve BR03 (DSM 16604)

Label Claim

Food supplement with probiotic strains.

Effective nutraceutical combination
Scientific Rationale
In vitro studies

Intestinal eubiosis is crucial for proper gut function and the overall well-being of the body. PROBIAL® KIDS Flora Forte is designed to help rebalance gut flora and restore physiological gut functions, featuring a high quantity of three different probiotic strains:

  • Lacticaseibacillus paracasei subsp. paracasei LPC00: This strain is known for its anti-inflammatory activity [1].

  • Lacticaseibacillus rhamnosus LR04: Characterized by its strong antipathogenic activity against various nosocomial pathogens and E. coli serotypes [2,3]. LR04 also has the capability to form a biofilm, offering protection from low pH environments, produce beneficial metabolites, and protect mature enterocytes in the small intestine [4].

  • Bifidobacterium breve BR03: Noted for its strong anti-inflammatory activity [5-8].

The formulation is provided in a hydrosoluble powder, making it easily consumable and suitable for children.

Bibliography

1. Internal Probiotical data

2. Mogna L. et al. Assessment of the in vitro inhibitory activity of specific probiotic bacteria against different Escherichia coli strains. J Clin Gastroenterol. 2012; 46 Suppl:S29-32

3.  Deidda F, et al. How Probiotics may Kill Harmful Bacteria: The in vitro Activity against Some Haemolytic Strains. J Prob Health, 2020. Vol. 8 Iss.2 No: 216.  DOI: 10.35248/2329-8901.20.8.216

4. Chamignon C, et al. Evaluation of the Probiotic Properties and the Capacity to Form Biofilms of Various Lactobacillus Strains. Microorganisms. 2020 Jul 15;8(7):1053  doi: 10.3390/microorganisms8071053.

5. Nicola S. et al. Interaction between probiotics and human immune cells: the prospective anti-inflammatory activity of Bifidobacterium breve BR03. AgroFOOD, 2010; 21(2):S44-47.

6. Bozzi Cionci N, et al. Therapeutic Microbiology: The Role of Bifidobacterium breve as Food Supplement for the Prevention/Treatment of Paediatric Diseases. Nutrients. 2018 Nov 10;10(11):1723. doi: 10.3390/nu10111723

7. Amoruso A. et al. A Systematic Evaluation of the Immunomodulatory and Functional Properties of Probiotic Bifidobacterium Breve BR03 (DSM 16604) Lactobacillus plantarum LP01 (LMG P-21021). J Prob Health. 2019;  7:214. Doi: 10.35248/2329-8901.19.7.214

8. Del Piano M., et al. In vitro sensitivity of probiotics to human pancreatic juice. J Clin Gastroenterol. 2008;42 Suppl 3 Pt 2:S170-S173. doi:10.1097/MCG.0b013e3181815976.

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