PROBIAL KIDS IMMUNE 2

PROBIAL® KIDS Immune 2 is specifically designed to bolster the immune system in children, offering protection against pathogen attacks and supporting energy metabolism. This formulation includes a blend of probiotic strains and vitamin D, each contributing unique benefits:

• Bifidobacterium infantis BI02: This strain is prominently present in the infant gut microbiota, playing a crucial role in maintaining a healthy microbial balance.

• Limosilactobacillus reuteri LRE02: Known for its antipathogenic activity against certain hemolytic strains, L. reuteri LRE02 also has the unique ability to produce vitamin B12. This is beneficial for mucosal health and aids in energy-yielding metabolism.

• Lactiplantibacillus plantarum LP14: This strain demonstrates strong direct inhibition against various nosocomial pathogens like Enterococcus faecalis, Klebsiella pneumoniae, E. coli, and Staphylococcus aureus, due to genes coding for bacteriocins [1]. Additionally, LP14 can inhibit the binding of the RBD of the spike proteins of SARS-CoV-2 to the human ACE2 receptor, a key pathway for viral entry into host cells [3]. LP14 also plays a role in protecting and restoring membrane integrity after damage induced by pro-inflammatory stimuli, which is particularly beneficial in preventing leaky gut—a condition that can exacerbate the severity of infections [2].

• Vitamin D: While primarily known for its role in calcium homeostasis, vitamin D3 also possesses immunostimulating and immunomodulating properties. It facilitates the proper absorption of calcium and phosphorus, essential for the development of bones and brain function.

The formulation of PROBIAL® KIDS Immune 2 is in orosoluble powder form, making it convenient for use even when away from home, ensuring easy administration for children.