Oral Care

Developed Formulas
Benefits
  • Supports a healthy oral microbiome
  • Helps reduce halitosis
Oral Care
Clinical test
Oral Care
In vitro test
Oral Care
Allergen Free
Oral Care
Real time stability
Oral Care
Orosoluble
Components

Lacticaseibacillus rhamnosus LR06 (DSM 21981)
Lactiplantibacillus pentosus LPS01 (DSM 21980)
Lactiplantibacillus plantarum LP01 (LMG P-21021)
Lactobacillus delbrueckii LDD01 (DSM 22106)

Label Claim

Food supplement with probiotic strains.

Effective nutraceutical combination

Vitamin D3
EFSA Claim: contributes to maintain normal teeth
Vitamin C
EFSA Claim: contributes to normal collagen formation for the normal function of gums

Scientific Rationale

Halitosis, commonly known as bad breath, is the third most common reason for seeking dental care, following dental caries and periodontal disease. Approximately 25% of the general population suffers from halitosis. The most prevalent cause of halitosis in the mouth is the formation of a halitogenic biofilm on the posterior dorsal tongue, as well as within gingival crevices and periodontal pockets.

ALITOLACTIS® is a probiotic product specifically developed to improve the qualitative and quantitative bacterial composition of the oral cavity. In a clinical study involving patients who were chronically treated with proton pump inhibitors (PPIs), ALITOLACTIS® demonstrated effectiveness in enhancing the oral microbiota in subjects with halitosis, particularly where the salivary microflora was initially compromised due to prolonged PPI use.

Following 15 days of treatment with ALITOLACTIS®, notable improvements were observed:

  • A significant improvement in oral microflora was noted, characterized by a reduction in total bacteria in saliva, a considerable reduction in coliforms and sulfite reducers, and a simultaneous increase in the lactobacilli load.

  • There were important reductions in hydrogen sulphide and mercaptans, which are key markers for halitosis. This resulted in a general improvement in halitosis symptoms, aligning the oral bacterial profiles closer to those of healthy subjects not treated with PPIs.

Bibliography

1. Chomyszyn-Gajewska M, Skrzypek A. Halitoza--diagnostyka i leczenie [Halitosis--diagnosis and treatment]. Przegl Lek. 2013;70(2):65-8. Polish.

2. Quirynen M, et al. Characteristics of 2000 patients who visited a halitosis clinic. J Clin Periodontol. 2009 Nov;36(11):970-5. Doi:  10.1111/j.1600-051X.2009.01478.x

3. Del Piano M. et al. Correlation between specific bacterial groups in the oral cavity and the severity of halitosis: any possible beneficial role for selected Lactobacilli? J Gastroint Dig Syst, 2014; 4:197.

Associations