Urology

Developed Formulas
Benefits
  • Helps prevent chronic bacterial prostatitis
  • Anti-pathogenic and anti-inflammatory activities
  • Degrades oxalates
Urology
Microbac
Urology
In vitro test
Urology
Allergen Free
Urology
Capsules
Components

Lactobacillus plantarum LP01 (LMG-21021)
Lactobacillus paracasei LPC09 (DSM 24243)
Zinc
Saw palmetto d.e.

Label Claim

Label claim (Europe)
Zinc contributes to the mainteinance of normal testosterone levels in the blood.

Effective nutraceutical combination
Scientific Rationale

BIFIPROST® is a specialized formulation combining selected probiotics, Serenoa repens (saw palmetto), and zinc to enhance prostate health. The two probiotic strains, Lactobacillus plantarum LP01 and Lactobacillus paracasei LPC09, are chosen for their ancillary properties:

  • Anti-inflammatory activity [1]
  • Inhibition of various E. coli strains, including the enterohemorrhagic E. coli O157:H7 [2,3].
  • Oxalate degradation activity [4].

Benign prostatic hyperplasia (BPH), a condition causing lower urinary tract symptoms (LUTS), is a frequent diagnosis in the aging male population, with its prevalence increasing with age.

Saw Palmetto: Research has shown the effectiveness of saw palmetto in alleviating symptoms associated with BPH. Its phytocomplex is commonly utilized at a dosage of 320 mg in various medicinal products [5].

Zinc: Essential for maintaining normal testosterone levels and protecting cells from oxidative stress, a key factor in BPH development. Zinc is a vital micronutrient for prostate health and in preventing prostate enlargement [6,7].

Bibliography

1. Amoruso A. et al. A Systematic Evaluation of the Immunomodulatory and Functional Properties of Probiotic Bifidobacterium Breve BR03 (DSM 16604) Lactobacillus plantarum LP01 (LMG P-21021). J Prob Health. 2019;  7:214. Doi: 10.35248/2329-8901.19.7.214.

2. Mogna L. et al. Assessment of the In Vitro Inhibitory Activity of Specific Probiotic Bacteria Against Different Escherichia coli strains. J. Clin. Gastroenterol. 2012;46 Suppl.S29-32. Doi: 10.1097/MCG.0b013e31826852b7

3. Deidda F, et al. How Probiotics may Kill Harmful Bacteria: The in vitro Activity against Some Haemolytic Strains. J Prob Health, 2020. Vol. 8 Iss.2 No: 216.  DOI: 10.35248/2329-8901.20.8.216

4. Mogna L, et al. Screening of different probiotic strains for their in vitro ability to metabolise oxalates: any prospective use in humans? J Clin Gastroenterol. 2014 Nov-Dec;48 Suppl 1:S91-5.

5. Lowe FC, Ku JC. Phytotherapy in treatment of benign prostatic hyperplasia: a critical review. Urology. 1996 Jul;48(1):12-20. doi: 10.1016/s0090-4295(96)00077-5

6. Deng C,  et al. [Clinical study of zinc for the treatment of chronic bacterial prostatitis]. Zhonghua Nan Ke Xue. 2004 May;10(5):368-70. 

7. Epstein MM,  et al. Dietary zinc and prostate cancer survival in a Swedish cohort. Am J Clin Nutr. 2011 Mar;93(3):586-93. doi: 10.3945/ajcn.110.004804

Associations