Developed Formulas
  • Limits the inflammatory response linked to training
  • Enhances performance throughout training and competition
  • Reduces muscle tension in the days post-workout
Ready to market
Clinical test
In vitro test
Allergen Free
Real time stability

Bifidobacterium breve BR03™ (DSM 16604)
Streptococcus thermophilus FP4 (DSM 18616)

Label Claim

Food supplement with probiotic strains.

Effective nutraceutical combination

EFSA Claim: increases physical performance in successive bursts of short-term, high intensity exercise (3g)

Scientific Rationale

A sedentary lifestyle, poor eating habits, and psychophysical distress are all factors contributing to intestinal dysbiosis [1]. The gut microbiota's ability to modulate pathophysiological processes means that intestinal dysbiosis can trigger various diseases. Consequently, probiotics, as modulators of gut microbiota, become crucial in promoting a healthy and active lifestyle [2]. They enhance the immune system, target gut health and intestinal barrier function, and offer anti-inflammatory and antioxidative benefits. Additionally, probiotics can improve physical performance and aid in post-workout recovery [3,4]. BIFISPORT® represents the first probiotic food supplement specifically developed and clinically tested to mitigate the inflammatory response associated with training and boost athletes' performance.

Combining Bifidobacterium breve BR03 and Streptococcus thermophilus FP4, BIFISPORT® is formulated and clinically tested to enhance the overall immune response of athletes, alleviate the reduction in immune defenses, limit the inflammatory response related to training, and augment performance during training and competition [5-8]. A clinical study involving resistance-trained men demonstrated that 3 weeks of supplementation with BIFISPORT® improved sports performance and reduced muscle tension post-exercise compared to a control group [8].


1. Redondo-Useros N, et al. Microbiota and Lifestyle: A Special Focus on Diet. Nutrients. 2020 Jun 15;12(6):1776. doi: 10.3390/nu12061776  

2. Aureli P, et al.Probiotics and health: an evidence-based review. Pharmacol Res. 2011 May;63(5):366-76. doi: 10.1016/j.phrs.2011.02.006

3. Ünsal C, et al. The effects of exhaustive swimming and probiotic administration in trained rats: Oxidative balance of selected organs, colon morphology, and contractility. Physiol Int. 2018 Dec 1;105(4):309-324. doi: 10.1556/2060.105.2018.4.25

4. Divella R, et al. Diet, Probiotics and Physical Activity: The Right Allies for a Healthy Microbiota. Anticancer Res. 2021 Jun;41(6):2759-2772. doi: 10.21873/anticanres.15057

5. Mogna L, et al. Assessment of the in vitro inhibitory activity of specific probiotic bacteria against different Escherichia coli strains. J Clin Gastroenterol. 2012 Oct;46 Suppl:S29-32. doi: 10.1097/MCG.0b013e31826852b7

6. Pane M, et al. Gut Microbiota, Probiotics, and Sport: From Clinical Evidence to Agonistic Performance. J Clin Gastroenterol. 2018 Nov/Dec;52 Suppl 1, Proceedings from the 9th Probiotics, Prebiotics and New Foods, Nutraceuticals and Botanicals for Nutrition & Human and Microbiota Health Meeting, held in Rome, Italy from September 10 to 12, 2017:S46-S49. doi: 10.1097/MCG.0000000000001058

7. Jäger R, et al.  International Society of Sports Nutrition Position Stand: Probiotics. J Int Soc Sports Nutr. 2019 Dec 21;16(1):62. doi: 10.1186/s12970-019-0329-0

8. Jäger R. et al. Probiotic Streptococcus thermophilus FP4 and Bifidobacterium breve BR03 Supplementation Attenuates Performance and Range-of-Motion Decrements Following Muscle Damaging Exercise. Nutrients. 2016 Oct 14;8(10). pii: E642.