PROBIAL CYS
Gynecology
- Supports the treatment and prevention of cystitis
- Counteracts intestinal permeability
- Selectively inhibits Escherichia coli
Lacticaseibacillus rhamnosus LR06 (DSM 21981)
Cranberry (Vaccinium macrocarpon Aiton), fruit, d.j.
Proanthocyanidins (PACs)
Food supplement with probiotic strains.
Biotin
EFSA Claim: contributes to the mantainance of normal mucosa
With approximately 150 million people affected globally each year, urinary tract infections (UTIs) rank as one of the most prevalent bacterial infections [1-3]. UTIs are attributed to a broad spectrum of pathogens, predominantly involving uropathogenic Escherichia coli (UPEC) [2,3]. PROBIAL® CYS is a supplement devised with a dual-action strategy to combat and prevent UTIs, thanks to:
Lacticaseibacillus rhamnosus LR06: Demonstrated in in vitro studies, LR06 has shown a strong and selective inhibition of E. coli growth, including the pathogenic serotype O157:H7 [4]. It also plays a role in restoring membrane integrity following damage induced by pro-inflammatory stimuli, aiding in countering leaky gut syndrome [5].
Cranberry d.e (dry extract): Notably rich in proanthocyanidins A, its phytocomplex is among the most clinically supported in terms of antimicrobial activity against E. coli [6].
The formulation is available in orosoluble powder, facilitating ease of use even when away from home, as well as in hydrosoluble powder form
1. Stamm WE, Norrby SR. Urinary tract infections: disease panorama and challenges. J Infect Dis. 2001 Mar 1;183 Suppl 1:S1-4. doi: 10.1086/318850.
2. Flores-Mireles AL, et al. Urinary tract infections: epidemiology, mechanisms of infection and treatment options. Nat Rev Microbiol. 2015 May;13(5):269-84. doi: 10.1038/nrmicro3432.
3. Foxman B. Urinary tract infection syndromes: occurrence, recurrence, bacteriology, risk factors, and disease burden. Infect Dis Clin North Am. 2014 Mar;28(1):1-13. doi: 10.1016/j.idc.2013.09.003.
4. Mogna L, et al. Assessment of the in vitro inhibitory activity of specific probiotic bacteria against different Escherichia coli strains. J Clin Gastroenterol. 2012 Oct;46 Suppl:S29-32. doi: 10.1097/MCG.0b013e31826852b7
5. Internal Probiotical data
6. Blumberg JB, et al. Cranberries and their bioactive constituents in human health. Adv Nutr. 2013 Nov 6;4(6):618-32. doi: 10.3945/an.113.004473
