Lacticaseibacillus rhamnosus LR05 (DSM 19739) (formerly Lactobacillus rhamnosus)
Allergy & Immunology
Immune stimulation / Respiratory infections
Reinforces the body’s natural defenses
Reduces intestinal discomfort
Inhibits intestinal and respiratory pathogens
1) 10 billion CFU + BS01™, LP02 + FOS
2) 250 million CFU + LR04, LP01™, LP02, BS01™ + FOS/GOS (BIFIVIR®) + colostrum
Single strain
Blend
Finished dosage form
1) Pregliasco F. et al. A New Chance of Preventing Winter Diseases by the Administration of Symbiotic Formulations. Journal of Clinical Gastroenterology, 2008; 42(2): 224-233. DOI: 10.1097/MCG.0b013e31817e1c91
2) Belcaro G. et al. Prevention of flu episodes with colostrum and Bifivir compared with vaccination: an epidemiological, registry study. Panminerva Medica 2010;52:269-75.
a) Visciglia A. et al. Probiotics: a potential therapeutic strategy in respiratory infections. Poster from the 12th Probiotics, Prebiotics & New Foods, Nutraceutical and Botanicals for Nutrition & Human and Microbiota Health, held in Rome on 12-14 September 2021
Allergy & Immunology
Grass pollen allergy
Beneficially modulates immunity
Stimulates anti-inflammatory IL-10 cytokine
Downregulates grass pollen extract-induced Th2 immune response
Single strain
Blend
Finished dosage form
a) Heldner A, et al. Ex Vivo Immunomodulatory Effects of Lactobacillus-, Lacticaseibacillus-, and Bifidobacterium-Containing Synbiotics on Human Peripheral Blood Mononuclear Cells and Monocyte-Derived Dendritic Cells in the Context of Grass Pollen Allergy. Probiotics Antimicrob Proteins. 2023 Aug;15(4):868-879. DOI: 10.1007/s12602-022-09920-w
Immunomodulation in vitro data available upon request
Dermatology
Atopic dermatitis
Reduces severity of atopic dermatitis
Decreases need for corticosteroids, antihistamines and calcineurin inhibitors
1) 1 billion encapsulated cells + BS01™ + FOS (PROBIAL® Skin Atopic)
Single strain
Blend
Finished dosage form
1) Manzotti G. et al. Probiotics as a Novel Adjuvant Approach to Atopic Dermatitis. J Contemp Immunol. 2014; 1(2): 57-66. DOI:10.7726/JCI.2014.1007
Healthy Aging
Elderly GI Health
Reduces constipation in elderly patients
1) 10 billion CFU
Single strain
Blend
Finished dosage form
1) Del Piano M. et al. The use of probiotics in the treatment of constipation in the elderly (BL03, LP01, BS01, LR05, BA02 and BR03 separately). CIBUS, 2005; 1(1):23-30.
