Ligilactobacillus salivarius CRL1328 (DSM 24441) (formerly Lactobacillus salivarius)
Gynecology
Urogenital health
Under worldwide exclusive license from the CEntro de REferencia para LActobacilos, Argentina
Supports vaginal health
Supports a healthy vaginal microbiota
Inhibits pathogenic Candida, Gonorrhea, E. faecalis, and E. faecium [in vitro]
Single strain
Blend
Finished dosage form
a) Ocana V. et al. Characterization of a bacteriocin like substance produced by a vaginal Lactobacillus salivarius strain. Applied and Environmental Microbiology, 1999; 65(12):5631-5635. DOI: 10.1128/AEM.65.12.5631-5635.1999
b) Ocana V. et al. Surface characteristics of Lactobacilli isolated from human vagina. J. Gen. Appl. Microbiol., 1999; 45:203-212. DOI: 10.2323/jgam.45.203
c) Tomas MSJ. et al. Influence of pH, temperature and culture media on the growth and bacteriocin production by vaginal Lactobacillus salivarius CRL 1328. Journal of Applied Microbiology, 2002; 93: 714-724. DOI: 10.1046/j.1365-2672.2002.01753.x
d) Gillor O. et al. The dual role of bacteriocins as anti- and probiotics. Appl Microbiol Biotechnol. 2008 December; 81(4): 591–606. DOI: 10.1007/s00253-008-1726-5
e) Dover S.E. et al. Natural antimicrobials and their role in vaginal health: a short review. Int J Probiotics Prebiotics. 2008 ; 3(4): 219–230.
f) Juárez Tomás M.S. et al. Viability of vaginal probiotic Lactobacilli during refrigerated and frozen storage. Anaerobe, Vol 10, Issue 1, February 2004, 1-5. DOI: 10.1016/j.anaerobe.2004.01.002
g) Zàrate G. and Nader-Macias ME. Influence of probiotic vaginal Lactobacilli on in vitro adhesion of urogenital pathogens to vaginal epithelial cells. Letters in Applied Microbiology ISSN 0266-8254. DOI: 10.1111/j.1472-765X.2006.01934.x
h) Ocana V and Nader-Macias ME. Adhesion of Lactobacillus Vaginal Strains with Probiotic Properties to Vaginal Epithelial Cells, 2011, Biocell 25(3):265-273.
i) Ocana V and Nader-Macias ME. Vaginal Lactobacilli: self and coaggregating ability, British Journal of Biomedical Science 2002, 59(4). DOI: 10.1080/09674845.2002.11783657
j) Tomas MSJ et al. Characterization of potentially probiotic vaginal Lactobacilli isolated from Argentinean women. British Journal of Biomedical Science 2005 62(4). DOI: 10.1080/09674845.2005.11732706
k) Vera Pingitore E. et al. Characterization of salivaricin CRL 1328, a twopeptide bacteriocin produced by Lactobacillus salivarius CRL 1328 isolated from the human vagina. Res Microbiol. 2009;160(6):401-408. DOI: 10.1016/j.resmic.2009.06.009
l) Vera Pingitore E. et al. Influence of vitamins and osmolites on growth and bacteriocin production by Lactobacillus salivarius CRL 1328 in a chemically defined medium. Can J Microbiol. 2009;55(3):304-310. DOI: 10.1139/w08-092
m) Vera Pingitore E. et al. Design of novel urogenital pharmabiotic formulations containing Lactobacilli, salivaricin CRL 1328 and non- microbial compounds with different functionalities. Drug Dev Ind Pharm. 2015;41(6):942-952. DOI: 10.3109/03639045.2014.917092
n) Vera Pingitore E. et al. Effect of lyophilization and storage temperature on the activity of salivaricin CRL 1328, a potential bioactive ingredient of a urogenital probiotic product. J Gen Appl Microbiol. 2012;58(2):71-81. DOI: 10.2323/jgam.58.71
